What makes us alone?

What makes us alone? I don`t mean, alone sometimes, but alone all the time? Why are some people always alone? What kind of alone? Well, the ones who are loners, who have friends that are only co-workers, penpals, newsgroupers. Seniors, the old forgotten ones or just second to their children's busy lives. The disfigured, the homeless, the freakish or just the extreames (no legs, retardation, lunatics, them people etc). The depressed or those that just want to be alone or them that just do not know why. What sorts of defenses do these unapproachable behold? Are they so strange looking or just uglificatting? No one would want to leave themselves open to hurt them, or not having to hurt them, or to witness a response from someone who, never responds, so it would be a safe assumption to, just not start anything with a shronic loner. You are the witness, having seen us. Seeing us is in some strange way, seeing your(self).